Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 6/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465703 | 0.90 | CACNA1H (0.40) | CACNA1HHRH3WNT3AKDM4EALDH1A1 | |
| SCHEMBL26467004 | 0.90 | CACNA1H (0.36) | CACNA1H | |
| SCHEMBL26465564 | 0.90 | CACNA1H (0.43) | CACNA1HKDM4EALDH1A1 | |
| SCHEMBL26465563 | 0.85 | CACNA1H (0.42) | CACNA1HKDM4EALDH1A1 | |
| SCHEMBL26466097 | 0.85 | CACNA1H (0.45) | CACNA1HKDM4EALDH1A1GLATDP1 | |
| SCHEMBL26465693 | 0.81 | CACNA1H (0.41) | CACNA1HWNT3AKDM4EALDH1A1GLA | |
| SCHEMBL26465825 | 0.81 | ALDH1A1 (0.44) | CACNA1HKDM4EALDH1A1 | |
| SCHEMBL26465818 | 0.80 | CACNA1H (0.42) | CACNA1HHRH3KDM4EALDH1A1GLA | |
| SCHEMBL26466922 | 0.79 | CACNA1H (0.41) | CACNA1HWNT3AKDM4EALDH1A1 | |
| SCHEMBL26466012 | 0.78 | CACNA1H (0.45) | CACNA1HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |