Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LHCGR | P22888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465825 | 0.91 | ALDH1A1 (0.44) | CACNA1HKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL26465703 | 0.90 | CACNA1H (0.40) | CACNA1HWNT3AEPHX2KMT2AMEN1 | |
| SCHEMBL26465688 | 0.86 | HPGD (0.53) | CACNA1HKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL26465813 | 0.86 | MAPT (0.43) | CACNA1HAKT1ALDH1A1KDM4EHPGD | |
| SCHEMBL26465818 | 0.85 | CACNA1H (0.42) | CACNA1HAKT1KMT2AMEN1ALDH1A1 | |
| SCHEMBL26465692 | 0.85 | CACNA1H (0.45) | CACNA1HAKT1WNT3AEPHX2KMT2A | |
| SCHEMBL26466001 | 0.83 | L3MBTL1 (0.48) | CACNA1HKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL26465564 | 0.82 | CACNA1H (0.43) | CACNA1HKMT2AMEN1ATMALDH1A1 | |
| SCHEMBL26464489 | 0.81 | CACNA1H (0.38) | CACNA1HWNT3AALDH1A1KDM4EGLA | |
| SCHEMBL26465080 | 0.80 | CACNA1H (0.56) | CACNA1HKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |