Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CES2 | O00748 | 2/20 | 0.30 |
| ▸ | CES1 | P23141 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085444 | 0.80 | AKT1 (0.38) | ATMTDP1TSHRALDH1A1CES2 | |
| SCHEMBL18792399 | 0.79 | ATM (0.37) | ATMTDP1TSHRPOLBMAPT | |
| SCHEMBL26482446 | 0.74 | TSHR (0.32) | ATMTDP1TSHRPOLBCYP3A4 | |
| SCHEMBL19101609 | 0.71 | TSHR (0.32) | ATMTDP1TSHRPOLBCYP3A4 | |
| SCHEMBL19300441 | 0.70 | AKT1 (0.38) | ATMTDP1TSHRMAPTL3MBTL1 | |
| SCHEMBL18871861 | 0.68 | ATM (0.35) | ATMTDP1TSHRPOLBMAPT | |
| SCHEMBL21389619 | 0.68 | HTR3E (0.48) | TDP1MAPTCYP2C19BLM | |
| SCHEMBL17620786 | 0.66 | KMT2A (0.33) | POLBMAPTRECQLL3MBTL1ALDH1A1 | |
| SCHEMBL9519534 | 0.66 | ALDH1A1 (0.38) | TDP1TSHRPOLBCYP3A4PARP1 | |
| SCHEMBL22861519 | 0.66 | KMT2A (0.50) | POLBCYP3A4MAPTCYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776968-B2 | Processes for producing cycloalkylcarboxamido-pyridine benzoic acids | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-10-03 | — | — | US | disclosed |
| US-20170158676-A9 | PROCESSES FOR PRODUCING CYCLOALKYLCARBOXAMIDO-PYRIDINE BENZOIC ACIDS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158676-A9 | PROCESSES FOR PRODUCING CYCLOALKYLCARBOXAMIDO-PYRIDINE BENZOIC ACIDS | DDC, PCCA, KMO | ATM 3103/4885TDP1 1684/4885TSHR 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.