Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512713 | 0.87 | ALDH1A1 (0.55) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL8760125 | 0.86 | CASP6 (0.62) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL13286800 | 0.85 | ALDH1A1 (0.56) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL21625555 | 0.83 | CTSD (0.63) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL1252136 | 0.83 | LMNA (0.68) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL3116351 | 0.83 | ALDH1A1 (0.50) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL31387585 | 0.82 | TSHR (0.66) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL13495683 | 0.82 | TSHR (0.66) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL764067 | 0.81 | PARP1 (0.67) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL1483661 | 0.81 | ALDH1A1 (0.56) | MAPK1ALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |