Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HTR2B | P41595 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26204080 | 0.83 | NR4A2 (0.64) | ALDH1A1KDM4EHTR2AMAPTKMT2A | |
| SCHEMBL3389562 | 0.81 | ALDH1A1 (0.61) | SPRALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL11793493 | 0.81 | F7 (0.53) | SPRALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL27471046 | 0.81 | GPR84 (0.58) | SPRALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL1081795 | 0.81 | F7 (0.66) | SPRALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL12720764 | 0.81 | SPR (0.56) | SPRALDH1A1NPSR1TSHRLMNA | |
| SCHEMBL7461248 | 0.80 | NHERF1 (0.51) | NPSR1LMNAMAPTKMT2ANHERF1 | |
| SCHEMBL7461028 | 0.80 | NHERF1 (0.48) | LMNANHERF1 | |
| SCHEMBL474836 | 0.78 | ALDH1A1 (0.66) | ALDH1A1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL21809188 | 0.78 | PBRM1 (0.61) | SPRALDH1A1NPSR1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |