Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.65 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.56 |
| ▸ | TUBB | P07437 | 1/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL31312793 | 0.98 | ALDH1A1 (0.64) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL24254359 | 0.88 | CFTR (0.68) | ALDH1A1ATMGABRA1GABRB2 | |
| SCHEMBL31411210 | 0.84 | GPR84 (0.67) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL3122183 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL5768987 | 0.82 | PBRM1 (0.66) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL28460337 | 0.81 | NR4A2 (0.69) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL12903051 | 0.81 | PBRM1 (0.60) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL7399821 | 0.81 | NR4A2 (0.63) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL7456891 | 0.81 | PBRM1 (0.69) | ALDH1A1ATMGPR84PBRM1NR4A2 | |
| SCHEMBL8251765 | 0.80 | GABRP (0.74) | NPC1RAB9AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036615-A | Indazole hydrazide compound and preparation method and application thereof | 南京农业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-118812539-A | 5-Aminotriazolopyrimidine derivative and preparation method thereof | 苏州大学 | 2024-10-22 | — | — | CN | claimed |
| CN-113087651-B | Compound containing indole group and preparation method and application thereof | 华南师范大学 | 2023-03-10 | — | — | CN | claimed |
| CN-115160209-A | Indole group-containing compound and preparation method and application thereof | 华南师范大学 | 2022-10-11 | — | — | CN | claimed |
| CN-111349088-B | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-111349080-B | Indole acylhydrazone compound, preparation method thereof and application of indole acylhydrazone compound in prevention and treatment of plant diseases | 天津师范大学 | 2022-08-26 | — | — | CN | claimed |
| CN-113562855-A | Environment-friendly efficient boiler water regulator for drum boiler | 浙江砉润科技有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113087651-A | Compound containing indole group and preparation method and application thereof | 华南师范大学 | 2021-07-09 | — | — | CN | claimed |
| CN-111689973-A | Dibenzocaprolactam pyrazolidine compound, preparation method and application | 朱翠萍 | 2020-09-22 | — | — | CN | claimed |
| CN-111349038-A | Indolylhydrazone compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| US-20030119860-A1 | METHOD FOR TRATMENT OF NON-RHEUMATOID ARTHRITIS | ELI LILLY AND COMPANY | 2003-06-26 | — | — | US | claimed |
| US-20030087944-A1 | Method for the treatment of renal dysfunction with spla2 inhibitors | CONCORD (HK) INTERNATIONAL EDUCATION LIMITED (HK) | 2003-05-08 | — | — | US | claimed |
| EP-1265607-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA 2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-12-18 | — | — | EP | claimed |
| WO-2001066111-A1 | COMPOSITIONS CONTAINING POTENTIAL SPLA2 INHIBITORS FOR THE TREATMENT OF PAIN | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | claimed |
| WO-2001066110-A2 | METHOD FOR THE TREATMENT OF RENAL DYSFUNCTION WITH sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-09-13 | — | — | WO | claimed |
| WO-2001055108-A2 | USE OF SPL A2 INHIBITORS FOR THE TREATMENT OF INFLAMMATION | ELI LILLY AND COMPANY (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1011670-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 2000-06-28 | — | — | EP | claimed |
| EP-1007056-A1 | METHOD FOR THE TREATMENT OF CYSTIC FIBROSIS | ELI LILLY AND COMPANY (US) | 2000-06-14 | — | — | EP | claimed |
| WO-1999016453-A1 | METHOD FOR THE TREATMENT OF CYSTIC FIBROSIS | ELI LILLY AND COMPANY (US) | 1999-04-08 | — | — | WO | claimed |
| WO-1999009978-A1 | METHOD FOR TREATMENT OF NON-RHEUMATOID ATHRITIS | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087944-A1 | Method for the treatment of renal dysfunction with spla2 inhibitors | IDO2, SPINT2, IDO1 | ALDH1A1 2210/4885ATM 4294/4885GPR84 1411/4885 |
| US-20030119860-A1 | METHOD FOR TRATMENT OF NON-RHEUMATOID ARTHRITIS | TPP2, PLAAT2, PLAA | ALDH1A1 1230/4885ATM 4767/4885GPR84 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.