Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662947 | 0.82 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL2647669 | 0.75 | METAP2 (0.35) | HSD11B1 | |
| SCHEMBL8418568 | 0.72 | NPSR1 (0.35) | — | |
| SCHEMBL8968442 | 0.70 | PPARA (0.37) | — | |
| SCHEMBL8968448 | 0.68 | CXCR2 (0.35) | — | |
| SCHEMBL8418567 | 0.67 | AKR1C3 (0.36) | — | |
| SCHEMBL27436177 | 0.66 | PPARA (0.39) | — | |
| SCHEMBL25620910 | 0.65 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL12151165 | 0.64 | GAA (0.34) | HSD11B1 | |
| SCHEMBL3292307 | 0.64 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |