Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26528469 | 0.83 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL31550492 | 0.79 | DPP4 (0.33) | DPP4DPP8DPP9DPP7SIRT2 | |
| SCHEMBL24642917 | 0.78 | DPP4 (0.48) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL24642558 | 0.74 | FAAH (0.34) | SIRT1SIRT6SIRT2SIRT3DRD2 | |
| SCHEMBL24642304 | 0.74 | ECE1 (0.36) | SIRT1SIRT6SIRT2SIRT3DRD2 | |
| SCHEMBL24642922 | 0.74 | SIRT1 (0.34) | SIRT1SIRT6SIRT2SIRT3DRD2 | |
| SCHEMBL24642680 | 0.74 | DPP4 (0.43) | DPP4DPP8DPP9DPP7SIRT2 | |
| SCHEMBL26496065 | 0.74 | MMP3 (0.33) | SIRT1SIRT6SIRT2SIRT3DRD2 | |
| SCHEMBL24642472 | 0.74 | SIRT1 (0.32) | SIRT1SIRT6SIRT2SIRT3DRD2 | |
| SCHEMBL26542866 | 0.73 | SIRT2 (0.33) | SIRT1SIRT6SIRT2SIRT3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |