Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892252 | 0.81 | CYP3A4 (0.53) | LMNAKDM4ECYP3A4ACHESLC6A4 | |
| SCHEMBL823757 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL31621879 | 0.80 | LMNA (0.52) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL2653694 | 0.79 | LMNA (0.44) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL27736846 | 0.79 | LMNA (0.44) | LMNAKDM4ECYP3A4ACHESLC6A4 | |
| SCHEMBL1432110 | 0.77 | ACHE (0.59) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL377567 | 0.77 | CYP3A4 (0.52) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL1824842 | 0.75 | LMNA (0.47) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL3331532 | 0.75 | CHRNA3 (0.49) | LMNAKDM4ECYP3A4ACHESLC6A4 | |
| SCHEMBL7959618 | 0.75 | LMNA (0.47) | LMNAKDM4ECYP3A4ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |