Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 7/20 | 0.56 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22958179 | 1.00 | P2RY14 (0.56) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL26114096 | 1.00 | P2RY14 (0.56) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| Hydrochloric Acid SCHEMBL4894283 | 0.98 | HTR2C (0.57) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| Hydrochloric Acid SCHEMBL4894281 | 0.98 | HTR2C (0.57) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL23873276 | 0.85 | P2RY14 (0.44) | P2RY14HTR2CSLC6A2SLC6A4 | |
| SCHEMBL26114503 | 0.85 | P2RY14 (0.44) | P2RY14HTR2CSLC6A2SLC6A4 | |
| SCHEMBL30075690 | 0.85 | P2RY14 (0.44) | P2RY14HTR2CSLC6A2SLC6A4 | |
| SCHEMBL9597729 | 0.85 | P2RY14 (0.44) | P2RY14HTR2CSLC6A2SLC6A4 | |
| SCHEMBL28537486 | 0.85 | HTR2C (0.47) | P2RY14HTR2CHTR2AHTR2BAKT1 | |
| SCHEMBL23873173 | 0.82 | HTR2C (0.60) | P2RY14HTR2CHTR2AHTR2BAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787798-B2 | Aryl piperidines as monoacylglycerol lipase modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787798-B2 | Aryl piperidines as monoacylglycerol lipase modulators | MGLL, LPL, PNLIP | P2RY14 1233/4885HTR2C 64/4885HTR2A 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.