Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26522945 | 0.78 | KMT2A (0.50) | KMT2AMEN1SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL26523081 | 0.78 | ALDH1A1 (0.50) | PYCR1ALDH1A1 | |
| SCHEMBL26522756 | 0.74 | POLB (0.49) | KMT2AMEN1PYCR1KDM4EALDH1A1 | |
| SCHEMBL1893045 | 0.65 | PYCR1 (0.52) | KMT2AMEN1PYCR1MAOBKDM4E | |
| SCHEMBL26522653 | 0.64 | KMT2A (0.45) | KMT2AMEN1PYCR1MAOBKDM4E | |
| SCHEMBL1239203 | 0.63 | HRH3 (0.59) | PYCR1HRH4HRH3MAOBSIGMAR1 | |
| SCHEMBL3132202 | 0.63 | ALDH1A1 (0.59) | PYCR1MAOBKDM4EALDH1A1 | |
| SCHEMBL26522610 | 0.63 | POLB (0.44) | KMT2APYCR1MAOBKDM4EALDH1A1 | |
| SCHEMBL19750331 | 0.63 | MEN1 (0.64) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL26383119 | 0.62 | POLB (0.52) | KMT2AMEN1MAOBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192506-A1 | MALT1 MODULATORS AND USES THEREOF | RARIFIED BIOSCIENCES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |