Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26524850 | 0.80 | LMNA (0.33) | NLRP3KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10615591 | 0.79 | ALDH1A1 (0.35) | NLRP3MAPK1KMT2AMEN1LMNA | |
| SCHEMBL24502399 | 0.78 | — | — | |
| SCHEMBL26524998 | 0.75 | MEN1 (0.32) | KMT2AMEN1LMNA | |
| SCHEMBL23323397 | 0.65 | — | — | |
| SCHEMBL10612763 | 0.64 | PLAU (0.35) | MAPK1KMT2AMEN1LMNAPLA2G1B | |
| SCHEMBL31587768 | 0.63 | GABRA1 (0.43) | NLRP3MAPK1KMT2AMEN1LMNA | |
| SCHEMBL7194598 | 0.63 | GABRA1 (0.43) | NLRP3MAPK1KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL10613086 | 0.63 | PKM (0.36) | MAPK1LMNA | |
| SCHEMBL11661495 | 0.63 | KMT2A (0.37) | NLRP3MAPK1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788038-B1 | KRAS G12C INHIBITORS AND METHODS OF USING THE SAME | AMGEN INC (US) | 2023-10-11 | — | — | EP | disclosed |