SCHEMBL26528181

SCHEMBL26528181

Cn1c2ccccc2c2ccc3c(c4cccc5c6ccccc6n3c54)c21

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.54
FTO Q9C0B1 1/20 0.54
GPR3 P46089 1/20 0.48
KDM4E B2RXH2 6/20 0.45
MAPT P10636 6/20 0.45
HSP90AA1 P07900 1/20 0.44
IDO1 P14902 1/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB1 P18505 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
GABRA4 P48169 1/20 0.43
GABRE P78334 1/20 0.43
GABRA6 Q16445 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21870426 0.92 ALKBH5 (0.50) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL24117559 0.88 ALKBH5 (0.53) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL25479545 0.87 GPR3 (0.53) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL26219894 0.86 KDM4E (0.42) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL26528357 0.86 RXRA (0.45) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL26528361 0.84 ALKBH5 (0.42) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL23131644 0.84 ALKBH5 (0.45) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL20857812 0.84 KDM4E (0.44) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL24434226 0.84 KDM4E (0.46) ALKBH5FTOGPR3KDM4EMAPT
SCHEMBL26528161 0.83 GPR3 (0.53) ALKBH5FTOGPR3KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 ALKBH5 1171/4885FTO 534/4885GPR3 4458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.