SCHEMBL26529047

SCHEMBL26529047

Cc1cc(C)cc(-c2cc(-c3cc(C)cc(C(F)(F)F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(C)cc(C(F)(F)F)c6)cc(-c6cc(C(F)(F)F)cc(C(F)(F)F)c6)c5)ccc3n4-c3ccccc3)c2)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ICMT O60725 9/20 0.40
RXRA P19793 5/20 0.39
RXRB P28702 5/20 0.39
RXRG P48443 3/20 0.37
MAT2A P31153 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PPARG P37231 1/20 0.34
NOTUM Q6P988 1/20 0.33
TEAD1 P28347 1/20 0.33
TEAD4 Q15561 1/20 0.33
TEAD2 Q15562 1/20 0.33
TEAD3 Q99594 1/20 0.33
TAS2R14 Q9NYV8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529348 0.87 ICMT (0.36) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26529036 0.87 KDM4E (0.46) RXRARXRBKDM4EATML3MBTL1
SCHEMBL26529498 0.86 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL26529085 0.85 RXRA (0.38) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26529563 0.85 GAA (0.36) ICMTRXRARXRBRXRGATM
SCHEMBL26529632 0.85 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL27440623 0.84 ABCG2 (0.36) ICMTMAT2A
SCHEMBL26529094 0.84 ALDH1A1 (0.36) ICMTRXRARXRBRXRGKDM4E
SCHEMBL26528984 0.84 ICMT (0.37) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26529015 0.83 ICMT (0.36) ICMTRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ICMT 36/4885RXRA 1633/4885RXRB 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.