Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 6/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019052 | 1.00 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL30675982 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL2653334 | 0.85 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL19283593 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL11817017 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL30610302 | 0.80 | XDH (0.53) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL28492133 | 0.80 | XDH (0.54) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 | |
| SCHEMBL7350821 | 0.79 | MEN1 (0.62) | ALDH1A1MEN1KMT2AL3MBTL1AGTR1 | |
| SCHEMBL24344787 | 0.78 | XDH (0.51) | ALDH1A1MEN1KMT2AL3MBTL1IDO1 | |
| SCHEMBL31419367 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2AL3MBTL1PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | HANGZHOU YIRUI PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-11-20 | — | — | US | claimed |
| EP-4538261-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hangzhou Yirui Pharmaceutical Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | claimed |
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | HANGZHOU YIRUI PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-11-20 | — | — | US | disclosed |
| EP-4538261-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hangzhou Yirui Pharmaceutical Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023237015-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 杭州壹瑞医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | BDKRB1, BDKRB2, UTS2R | ALDH1A1 2190/4885MEN1 1907/4885KMT2A 2463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.