Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31238056 | 1.00 | TDP1 (0.51) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL265689 | 0.90 | MAPT (0.45) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL264917 | 0.86 | TDP1 (0.50) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL265717 | 0.81 | MEN1 (0.44) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL266414 | 0.79 | MAPT (0.43) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL266697 | 0.76 | TDP1 (0.56) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL266219 | 0.76 | MAPT (0.38) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL265773 | 0.73 | LMNA (0.46) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL266574 | 0.73 | MEN1 (0.70) | TDP1TSHRMEN1KMT2AMAPT | |
| SCHEMBL7515416 | 0.71 | ALDH1A1 (0.57) | TDP1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655070-B1 | OXIDATION CATALYST | ASAHI KASEI CHEMICALS CORP (JP) | 2015-07-15 | — | — | EP | claimed |
| US-8133834-B2 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-13 | — | — | US | claimed |
| US-20060229471-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-10-12 | — | — | US | claimed |
| EP-1655070-A1 | OXIDATION CATALYST | Asahi Kasei Chemicals Corporation (JP) | 2006-05-10 | — | — | EP | claimed |
| EP-1655070-B1 | OXIDATION CATALYST | ASAHI KASEI CHEMICALS CORP (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-8785419-B2 | Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-07-22 | — | — | US | disclosed |
| US-8133834-B2 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8133834-B2 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| US-8019557-B2 | Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100151507-A1 | Cavity Induced Allosteric Modification Of Intermolecular Interactions And Methods Of Identifying Compounds That Effect The Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-06-17 | — | — | US | disclosed |
| US-20100069670-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100069670-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7653495-B1 | Comprises series of steps including identifying cavity proximal to functional critical site, determining physical parameters of cavity, identifying functional groups which can be accommodated by cavity, testing compounds comprising such functional groups in an in vitro assay to determine which are active | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-26 | — | — | US | disclosed |
| US-20060229471-A1 | Oxidation catalyst | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1655070-A1 | OXIDATION CATALYST | Asahi Kasei Chemicals Corporation (JP) | 2006-05-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069670-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | TDP1 2260/4885TSHR 4696/4885MEN1 4765/4885 |
| US-20060229471-A1 | Oxidation catalyst | PPOX, SOD1, HAO2 | TDP1 2260/4885TSHR 4696/4885MEN1 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.