SCHEMBL26548142

SCHEMBL26548142

Fc1ccc(-c2ccc3cc(-c4ccc(-c5ccc(C(F)(F)F)cc5)cc4)ccc3c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 13/20 0.50
PGR P06401 2/20 0.44
SLC6A2 P23975 1/20 0.44
P2RY14 Q15391 1/20 0.44
PIK3CA P42336 1/20 0.43
NR3C1 P04150 1/20 0.42
AGXT P21549 1/20 0.41
NPY5R Q15761 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548129 1.00 KIF11 (0.50) KIF11PGRSLC6A2P2RY14PIK3CA
SCHEMBL26548512 1.00 KIF11 (0.50) KIF11PGRSLC6A2P2RY14PIK3CA
SCHEMBL26548998 0.94 KIF11 (0.48) KIF11PGRSLC6A2P2RY14PIK3CA
SCHEMBL26548662 0.94 KIF11 (0.48) KIF11PGRSLC6A2P2RY14PIK3CA
SCHEMBL26548656 0.94 KIF11 (0.48) KIF11PGRSLC6A2P2RY14PIK3CA
SCHEMBL26548146 0.91 KIF11 (0.58) KIF11SLC6A2P2RY14AGXT
SCHEMBL26548524 0.91 KIF11 (0.58) KIF11SLC6A2P2RY14AGXT
SCHEMBL26548516 0.88 RXRA (0.49) KIF11PGRNR3C1
SCHEMBL26548138 0.88 RXRA (0.49) KIF11PGRNR3C1
SCHEMBL26548161 0.88 RXRA (0.49) KIF11PGRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 KIF11 3675/4885PGR 4012/4885SLC6A2 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.