SCHEMBL26548696

SCHEMBL26548696

FC(F)(F)c1ccc(-c2ccc3ccc(-c4ccc(-c5cccc6ccccc56)nc4)cc3c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.40
PIM1 P11309 1/20 0.38
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
IDO1 P14902 1/20 0.37
TDO2 P48775 1/20 0.37
KIF11 P52732 1/20 0.37
ALOX5AP P20292 1/20 0.37
FEN1 P39748 1/20 0.37
TOP1 P11387 2/20 0.37
CCNT1 O60563 1/20 0.36
CCNA2 P20248 1/20 0.36
CDK2 P24941 1/20 0.36
CDK9 P50750 1/20 0.36
MAOB P27338 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36
ENPP1 P22413 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548182 0.96 TRPV1 (0.41) TRPV1PIM1CYP11B1CYP11B2IDO1
SCHEMBL26548699 0.92 TDP1 (0.40) TRPV1PIM1CYP11B1CYP11B2IDO1
SCHEMBL26549200 0.91 PDGFRB (0.39) TRPV1TOP1CCNT1CCNA2CDK2
SCHEMBL26548184 0.88 TDP1 (0.40) TRPV1PIM1CYP11B1CYP11B2IDO1
SCHEMBL26548693 0.86 CASP3 (0.45) PIM1CYP11B1CYP11B2L3MBTL1
SCHEMBL26548689 0.84 KIF11 (0.43) TRPV1CYP11B1CYP11B2IDO1TDO2
SCHEMBL26548876 0.84 CA12 (0.47) TRPV1KIF11TOP1ENPP1
SCHEMBL26548564 0.84 CA12 (0.47) TRPV1KIF11TOP1ENPP1
SCHEMBL26567174 0.84 CYP11B1 (0.43) PIM1CYP11B1CYP11B2HPGDENPP1
SCHEMBL26548176 0.83 KIF11 (0.44) TRPV1CYP11B1CYP11B2IDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 TRPV1 885/4885PIM1 1158/4885CYP11B1 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.