SCHEMBL26567207

SCHEMBL26567207

CCc1cc(-c2ccc3ccc(-c4ccc(-c5cccc6ccccc56)nc4)cc3c2)cc(C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.36
CYP11B2 P19099 3/20 0.36
HTR2C P28335 2/20 0.33
HPGD P15428 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
PIM1 P11309 1/20 0.33
ALOX5AP P20292 1/20 0.32
FEN1 P39748 1/20 0.32
PARP1 P09874 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26548699 0.90 TDP1 (0.40) CYP11B1CYP11B2HPGDTDP1PIM1
SCHEMBL26567171 0.87 CYP11B1 (0.40) CYP11B1CYP11B2TDP1ALOX5APFEN1
SCHEMBL26567383 0.86 TOP1 (0.36) HTR2CALOX5APFEN1PARP1
SCHEMBL26553076 0.86 CA12 (0.38) HTR2CCYP1A2CYP2A6
SCHEMBL26567691 0.86 ALOX5 (0.35) CYP11B1CYP11B2
SCHEMBL26548184 0.86 TDP1 (0.40) CYP11B1CYP11B2HPGDTDP1PIM1
SCHEMBL26567180 0.84 CYP11B1 (0.45) CYP11B1CYP11B2HTR2CPIM1CYP1A2
SCHEMBL26548696 0.84 TRPV1 (0.40) CYP11B1CYP11B2HPGDPIM1ALOX5AP
SCHEMBL26567350 0.84 PTGS1 (0.38) CYP11B1CYP11B2ALOX5APFEN1CYP1A2
SCHEMBL26567266 0.83 SMN1; SMN2 (0.38) CYP11B1CYP11B2HPGDALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME LAPTO CO., LTD. (KR) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337527-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AOC1, ODC1, PIEZO1 CYP11B1 1676/4885CYP11B2 1913/4885HTR2C 4038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.