Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17718447 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ACHEHSD17B10HTR2A | |
| SCHEMBL27233654 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2ACHEHSD17B10HTR2A | |
| SCHEMBL2655142 | 0.81 | KDM1A (0.48) | HTR2AHTR2CHTR2BFBP1SLC6A2 | |
| SCHEMBL12242256 | 0.81 | KDM1A (0.48) | HTR2CHTR2BCYP2C9CYP2C19 | |
| SCHEMBL12860014 | 0.81 | KDM1A (0.48) | HTR2CHTR2BCYP2C9CYP2C19 | |
| SCHEMBL1524088 | 0.81 | KDM1A (0.48) | HTR2CHTR2BCYP2C9CYP2C19 | |
| SCHEMBL1524090 | 0.81 | KDM1A (0.48) | HTR2CHTR2BCYP2C9CYP2C19 | |
| SCHEMBL6940485 | 0.80 | MAOB (0.45) | ALDH1A1SMN1; SMN2HSD17B10HTR2AHTR2C | |
| SCHEMBL12242249 | 0.80 | MAOB (0.45) | ALDH1A1SMN1; SMN2HSD17B10HTR2AHTR2C | |
| SCHEMBL28135209 | 0.80 | MAOB (0.45) | ALDH1A1SMN1; SMN2HSD17B10HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160045456-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2016-02-18 | — | — | US | disclosed |
| US-20150368186-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | ORYZON GENOMICS S.A. | 2015-12-24 | — | — | US | disclosed |
| US-9149447-B2 | Lysine specific demethylase-1 inhibitors and their use | ORYZON GENOMICS S.A. (ES) | 2015-10-06 | — | — | US | disclosed |
| US-8993808-B2 | Phenylcyclopropylamine derivatives and their medical use | ORYZON GENOMICS, S.A. (ES) | 2015-03-31 | — | — | US | disclosed |
| US-8859555-B2 | Lysine Specific Demethylase-1 inhibitors and their use | ORYZON GENOMICS S.A. (ES) | 2014-10-14 | — | — | US | disclosed |
| US-20140213657-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | ORYZON GENOMICS S.A. (ES) | 2014-07-31 | — | — | US | disclosed |
| US-8722743-B2 | Lysine specific demethylase-1 inhibitors and their use | ORYZON GENOMICS S.A. (ES) | 2014-05-13 | — | — | US | disclosed |
| US-8524717-B2 | Oxidase inhibitors and their use | ORYZON GENOMICS, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |
| US-20130090386-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | ORYZON GENOMICS S.A. | 2013-04-11 | — | — | US | disclosed |
| US-20120283266-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | ORYZON GENOMICS S.A. (ES) | 2012-11-08 | — | — | US | disclosed |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS, S.A. (ES) | 2012-01-05 | — | — | US | disclosed |
| US-20110263604-A1 | Oxidase inhibitors and their use | ORYZON GENOMICS, S.A. (ES) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263604-A1 | Oxidase inhibitors and their use | MAOA, PNPO, MAOB | ALDH1A1 127/4885SMN1; SMN2 2782/4885ACHE 251/4885 |
| US-20120283266-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | JMJD6, KDM3A, KDM1A | ALDH1A1 502/4885SMN1; SMN2 4326/4885ACHE 2390/4885 |
| US-20150368186-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | KDM1A, KDM1B, KDM3A | ALDH1A1 256/4885SMN1; SMN2 4137/4885ACHE 2596/4885 |
| US-20130090386-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | KDM1A, KDM1B, KDM3A | ALDH1A1 255/4885SMN1; SMN2 4142/4885ACHE 2594/4885 |
| US-20140213657-A1 | LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE | KDM1A, KDM1B, KDM3A | ALDH1A1 236/4885SMN1; SMN2 4159/4885ACHE 2543/4885 |
| US-20120004262-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | ALDH1A1 1344/4885SMN1; SMN2 158/4885ACHE 86/4885 |
| US-20160045456-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | PNMT, ABCB1, SNCA | ALDH1A1 1344/4885SMN1; SMN2 158/4885ACHE 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.