Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28050862 | 0.85 | SHBG (0.38) | LMNAKDM4EALDH1A1GAAMAPT | |
| SCHEMBL21031355 | 0.83 | TAAR1 (0.35) | LMNATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL23131742 | 0.80 | LMNA (0.40) | LMNAMAPTSHBG | |
| SCHEMBL26568615 | 0.80 | LMNA (0.40) | LMNAALDH1A1MAPT | |
| SCHEMBL111999 | 0.79 | HRH3 (0.40) | LMNATAAR1KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7894748 | 0.77 | LMNA (0.42) | LMNATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL12622553 | 0.77 | ALDH1A1 (0.45) | LMNAKDM4EALDH1A1SHBGPRSS1 | |
| SCHEMBL5739230 | 0.76 | KDM4E (0.37) | LMNATAAR1KDM4EALDH1A1GAA | |
| SCHEMBL5530071 | 0.76 | NOS2 (0.38) | LMNATAAR1KDM4EALDH1A1HRH3 | |
| SCHEMBL14449432 | 0.75 | SHBG (0.32) | GAASHBGHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |