Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21031354 | 0.85 | PNMT (0.33) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL26566902 | 0.80 | LMNA (0.42) | LMNAALDH1A1MAPT | |
| SCHEMBL15129222 | 0.80 | CYP1A2 (0.37) | LMNATSHRALDH1A1DPP4 | |
| SCHEMBL29912653 | 0.77 | LMNA (0.33) | LMNADPP4 | |
| SCHEMBL22829991 | 0.77 | LMNA (0.33) | LMNADPP4 | |
| SCHEMBL320641 | 0.77 | TSHR (0.37) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL26566694 | 0.75 | TSHR (0.38) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL12622553 | 0.74 | ALDH1A1 (0.45) | LMNAALDH1A1 | |
| SCHEMBL4444016 | 0.74 | SHBG (0.44) | LMNATSHRALDH1A1MAPT | |
| SCHEMBL23131742 | 0.73 | LMNA (0.40) | LMNAMAPTDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609868-B1 | TETRAHYDROQUINOLINE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2023-10-18 | — | — | EP | disclosed |