SCHEMBL26569849

SCHEMBL26569849

Cc1cc(-n2cccc2)cc(-n2cccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
KDM4E B2RXH2 3/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
POLB P06746 7/20 0.38
APP P05067 1/20 0.37
ALDH1A1 P00352 4/20 0.37
HSP90AA1 P07900 1/20 0.36
CCR6 P51684 1/20 0.36
VHL P40337 1/20 0.34
ELOC Q15369 1/20 0.34
ELOB Q15370 1/20 0.34
HPGD P15428 2/20 0.34
HTT P42858 2/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
HSD17B10 Q99714 2/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5604589 0.94 MAPT (0.44) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL3466782 0.84 ALDH1A1 (0.52) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL1966595 0.77 MAPT (0.56) MAPTL3MBTL1KDM4EGAAALDH1A1
SCHEMBL12369610 0.74 CHRNB2 (0.44) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL1366622 0.72 L3MBTL1 (0.56) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL20319187 0.71 MAPT (0.68) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL2960961 0.70 POLB (0.39) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL9337373 0.67 MAPT (0.39) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL28844263 0.65 MAPT (0.38) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL28871084 0.65 MAPT (0.43) MAPTL3MBTL1KDM4EGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXER1 MAPT 773/4885L3MBTL1 356/4885KDM4E 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.