SCHEMBL28844263

SCHEMBL28844263

Fc1cc(-n2cccc2)cc(F)c1F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
KAT2B Q92831 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
VHL P40337 1/20 0.33
ELOC Q15369 1/20 0.33
ELOB Q15370 1/20 0.33
DNMT1 P26358 1/20 0.33
CASP6 P55212 1/20 0.33
MCL1 Q07820 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
GAA P10253 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
AKR1B1 P15121 1/20 0.33
ALDH1A1 P00352 3/20 0.31
POLB P06746 2/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9337322 0.74 CA1 (0.31)
SCHEMBL13735557 0.70 KDM4E (0.50) MAPTL3MBTL1KDM4ENPC1RAB9A
SCHEMBL5716054 0.70 ALDH1A1 (0.34) MAPTKDM4ENPC1GAANPSR1
SCHEMBL4798611 0.67 KAT2B (0.35) KAT2BCES2CES1
SCHEMBL4495221 0.66 ALDH1A1 (0.35) MAPTKDM4EGAAALDH1A1PKM
SCHEMBL7536022 0.65 MAPT (0.56) MAPTL3MBTL1NPC1RAB9ADNMT1
SCHEMBL5604589 0.65 MAPT (0.44) MAPTL3MBTL1KDM4EVHLELOC
SCHEMBL2239811 0.65 ALDH1A1 (0.56) MAPTL3MBTL1KDM4ENPC1RAB9A
SCHEMBL26569849 0.65 MAPT (0.39) MAPTL3MBTL1KDM4ENPC1RAB9A
SCHEMBL28165601 0.63 CES2 (0.30) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106654032-A Monolayer full-phosphorescence white-light organic electroluminescent device and preparation method thereof 苏州大学 2017-05-10 CN claimed