SCHEMBL26570948

SCHEMBL26570948

C[Si](C)(O)CCCc1ccc(C2C(c3ccccc3)C2c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.39
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
ADRA2A P08913 1/20 0.36
CHRM1 P11229 1/20 0.36
DRD1 P21728 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
OPRM1 P35372 1/20 0.36
DRD3 P35462 1/20 0.36
SLC6A3 Q01959 1/20 0.36
KCNH2 Q12809 1/20 0.36
AOC3 Q16853 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
HTR2A P28223 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
IGF1R P08069 1/20 0.35
ALOX15 P16050 1/20 0.35
P2RX7 Q99572 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4494444 0.84 HDAC3 (0.47) ADRA1ASLC6A3SIGMAR1
SCHEMBL27043275 0.77 MAPT (0.36) MAOBADRA1ASLC6A3HTR2ASIGMAR1
SCHEMBL680098 0.72 TDP1 (0.54) KCNH2TAAR1HTR2AALOX15
SCHEMBL16216219 0.68 L3MBTL1 (0.48) MAOBCHRM2HTR1AADRA2ACHRM1
SCHEMBL9745882 0.68 HDAC3 (0.50) MAOBADRA1ASLC6A3HTR2ASIGMAR1
SCHEMBL19180885 0.67 SIGMAR1 (0.52) MAOBADRA1ASLC6A3HTR2ASIGMAR1
SCHEMBL5804123 0.66 ADRA1A (0.46) CHRM2HTR1AADRA2ACHRM1DRD1
SCHEMBL5804462 0.66 SIGMAR1 (0.50) MAOBSIGMAR1
SCHEMBL18272631 0.66 CHRM2 (0.46) MAOBCHRM2HTR1AADRA2ACHRM1
SCHEMBL4494440 0.65 ADRA1A (0.47) CHRM2HTR1AADRA2ACHRM1DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4261214-A1 PHOTOACID GENERATOR, AND PHOTOSENSITIVE COMPOSITION USING SAME San-Apro Ltd. (JP) 2023-10-18 EP disclosed