Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266596 | 0.74 | KDM4A (0.44) | KDM4AKDM4ELMNACA12CA1 | |
| SCHEMBL21411397 | 0.73 | HDAC1 (0.38) | KDM4AKDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL21411380 | 0.72 | KDM4E (0.46) | KDM4AKDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL31751451 | 0.71 | KDM4A (0.38) | KDM4ACA1CA2L3MBTL1TDP1 | |
| SCHEMBL18136849 | 0.70 | KDM4A (0.41) | KDM4AKDM4ELMNAGAAL3MBTL1 | |
| SCHEMBL30466780 | 0.69 | ALDH1A1 (0.48) | KDM4AKDM4ELMNACA12CA1 | |
| SCHEMBL26759908 | 0.68 | L3MBTL1 (0.39) | KDM4AKDM4ELMNACA12CA1 | |
| SCHEMBL14877950 | 0.68 | KDM4A (0.47) | KDM4AKDM4ELMNACA12CA1 | |
| SCHEMBL31486392 | 0.68 | KDM4A (0.44) | KDM4AKDM4ELMNACA12CA1 | |
| SCHEMBL14036623 | 0.68 | KDM4A (0.44) | KDM4AKDM4ELMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |