Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.45 |
| ▸ | CBFB | Q13951 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | NEK2 | P51955 | 2/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | PRF1 | P14222 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16718767 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL28940758 | 0.81 | GPR52 (0.42) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL16718820 | 0.80 | CHEK1 (0.43) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL2659245 | 0.80 | BCAT2 (0.49) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL4996647 | 0.76 | MKNK1 (0.50) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL16718821 | 0.73 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL9133011 | 0.67 | CSNK2A1 (0.51) | ALDH1A1GAAMAPTHPGDHTT | |
| SCHEMBL16718819 | 0.67 | WDR5 (0.44) | ALDH1A1GAAMAPTHTTMEN1 | |
| SCHEMBL16718822 | 0.66 | PARP1 (0.40) | GAA | |
| SCHEMBL9135746 | 0.66 | MAPT (0.51) | ALDH1A1GAAMAPTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948458-A1 | BTK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-12-02 | — | — | EP | claimed |
| WO-2014114185-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-07-31 | — | — | WO | claimed |
| EP-3082821-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions, Inc. (US) | 2016-10-26 | — | — | EP | disclosed |
| EP-2948458-A1 | BTK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-12-02 | — | — | EP | disclosed |
| WO-2015073797-A1 | ANTIPARASITIC COMPOUNDS | SCYNEXIS INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| WO-2014114185-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2014-07-31 | — | — | WO | disclosed |
| EP-1794156-A2 | TROMBOPOIETIN RECEPTOR AGONISTS | Pfizer Products Incorporated (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1718624-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS GLUCOKINASE ACTIVATING AGENTS | AstraZeneca AB (SE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2006033005-A2 | THROMBOPOIETIN RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005080359-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS GLUCOKINAE ACTIVATING AGENTS | ASTRAZENECA AB (SE) | 2005-09-01 | — | — | WO | disclosed |