Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.30 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660574 | 0.91 | CDK1 (0.33) | CDK1CCNB1HRH4LGALS8LGALS3 | |
| SCHEMBL2659861 | 0.87 | DAO (0.39) | CDK1CCNB1LGALS8LGALS3 | |
| SCHEMBL2659102 | 0.84 | CDK1 (0.48) | CDK1CCNB1LGALS8LGALS3 | |
| SCHEMBL2660619 | 0.82 | FBP1 (0.35) | — | |
| SCHEMBL1653120 | 0.82 | CCR2 (0.43) | — | |
| SCHEMBL2661534 | 0.82 | TUBB4A (0.36) | HRH4 | |
| SCHEMBL2659460 | 0.80 | MEN1 (0.34) | HRH4 | |
| SCHEMBL2659039 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL2661101 | 0.73 | FBP1 (0.37) | — | |
| SCHEMBL1654437 | 0.72 | CCR2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |