Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.35 |
| ▸ | BRD1 | O95696 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.34 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15797658 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL26596827 | 0.70 | FAAH (0.33) | MEN1KMT2ABRPF1BRD1BRD4 | |
| SCHEMBL15804098 | 0.70 | BRPF1 (0.40) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30903880 | 0.66 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL31575236 | 0.66 | KDM4E (0.35) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27238839 | 0.66 | ALDH1A1 (0.38) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL25778228 | 0.66 | YTHDF2 (0.35) | BRPF1BRD4BRD9CA12CA9 | |
| SCHEMBL15804100 | 0.65 | BRPF1 (0.40) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL23900598 | 0.63 | KDM4E (0.53) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL11307956 | 0.63 | KDM4E (0.53) | KDM4EALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795172-B2 | Substituted imidazo[1,2-b]pyridazines and [1,2,4]triazolo[4,3-b]pyridazines as CaMKII inhibitors | CARDURION PHARMACEUTICALS, INC. (US) | 2023-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795172-B2 | Substituted imidazo[1,2-b]pyridazines and [1,2,4]triazolo[4,3-b]pyridazines as CaMKII inhibitors | CAMK2B, RYR2, CAMK2A | KDM4E 3921/4885ALDH1A1 1868/4885GAA 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.