Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2659721 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2659765 | 0.77 | RIPK1 (0.40) | SLC6A2SLC6A4SLC6A3PYCR1 | |
| SCHEMBL2659742 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12251062 | 0.67 | SIGMAR1 (0.54) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27014466 | 0.67 | PYCR1 (0.54) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20022001 | 0.67 | CYP1A2 (0.61) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2660478 | 0.67 | SLC6A2 (0.56) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17447228 | 0.66 | PYCR1 (0.61) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22912456 | 0.66 | BCHE (0.54) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23423745 | 0.65 | PYCR1 (0.65) | CYP1A2CYP2A6SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GPR119, GCGR | CYP1A2 1399/4885CYP2A6 1896/4885SLC6A2 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.