Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26599152 | 0.85 | MGAM (0.43) | CYP3A4MGAMGAASIMGAM2 | |
| SCHEMBL22717443 | 0.81 | MBOAT4 (0.40) | CYP3A4MGAMGAASIMGAM2 | |
| SCHEMBL22717882 | 0.80 | ALDH1A1 (0.54) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL22717376 | 0.80 | NPC1 (0.46) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL22717835 | 0.80 | PTGS1 (0.50) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL22717405 | 0.80 | ALDH1A1 (0.54) | MAOBMGAMGAASIMGAM2 | |
| SCHEMBL22717942 | 0.78 | MGAM (0.36) | CYP3A4MGAMGAASIMGAM2 | |
| SCHEMBL24500409 | 0.76 | MGAM (0.40) | MGAMGAASIMGAM2RAB9A | |
| SCHEMBL22717603 | 0.75 | MGAM (0.40) | CYP3A4MAOBMGAMGAASI | |
| SCHEMBL25153570 | 0.74 | RAB9A (0.58) | CYP3A4MAOBMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974043-A | Polq inhibitor compounds and uses thereof | 南京再明医药有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023202623-A1 | POLQ INHIBITOR COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2023-10-26 | — | — | WO | disclosed |