Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 8/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 8/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | MYT1 | Q01538 | 3/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30625142 | 0.84 | NR1H2 (0.38) | CDK1MYT1 | |
| SCHEMBL29261335 | 0.79 | PRMT5 (0.36) | PRMT5WDR77CDK1MYT1CREBBP | |
| SCHEMBL28558608 | 0.75 | CREBBP (0.34) | PRMT5WDR77CDK1MYT1CREBBP | |
| SCHEMBL26645670 | 0.71 | PRMT5 (0.41) | PRMT5WDR77CREBBPCSNK1DCSNK1E | |
| SCHEMBL20595880 | 0.68 | CREBBP (0.42) | PRMT5WDR77CREBBP | |
| SCHEMBL17925617 | 0.67 | CREBBP (0.34) | PRMT5WDR77CDK1MYT1CREBBP | |
| SCHEMBL20596105 | 0.67 | CREBBP (0.34) | PRMT5WDR77CDK1MYT1CREBBP | |
| SCHEMBL17925769 | 0.66 | FAAH (0.42) | CSNK1D | |
| SCHEMBL23705926 | 0.65 | DRD2 (0.39) | PRMT5WDR77CREBBP | |
| SCHEMBL30913152 | 0.64 | POLB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205680-A1 | PI3Kα INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |