Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 9/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660852 | 0.88 | PLA2G7 (0.33) | PLA2G7MCL1LMNAPOLBS1PR4 | |
| SCHEMBL2659747 | 0.87 | MCL1 (0.31) | MCL1 | |
| SCHEMBL2661327 | 0.86 | PLA2G7 (0.31) | PLA2G7LMNAPOLBS1PR4S1PR5 | |
| SCHEMBL2660524 | 0.82 | RAB9A (0.35) | MCL1LMNAPOLB | |
| SCHEMBL2660811 | 0.78 | TP53 (0.35) | LMNAPOLB | |
| SCHEMBL2660563 | 0.77 | HDAC3 (0.36) | PLA2G7 | |
| SCHEMBL2659767 | 0.76 | PYGL (0.32) | MCL1LMNAPOLB | |
| SCHEMBL2660397 | 0.76 | MCL1 (0.31) | MCL1 | |
| SCHEMBL2668575 | 0.76 | BCL2A1 (0.41) | MCL1LMNAPOLB | |
| SCHEMBL2660519 | 0.76 | HDAC3 (0.35) | PLA2G7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |