Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BID | P55957 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661327 | 0.90 | PLA2G7 (0.31) | MEN1KMT2ALMNAPOLB | |
| SCHEMBL2659947 | 0.88 | ALDH1A1 (0.40) | BCL2A1MCL1BCL2BIDBCL2L1 | |
| SCHEMBL2661328 | 0.85 | TP53 (0.35) | ALDH1A1FBP1MAPTMEN1KMT2A | |
| SCHEMBL2660519 | 0.79 | HDAC3 (0.35) | MAPTTP53LMNATHRB | |
| SCHEMBL2661002 | 0.77 | LGALS8 (0.32) | MAPTMEN1KMT2A | |
| SCHEMBL2660521 | 0.77 | PLCG2 (0.37) | ALDH1A1FBP1MAPTMEN1KMT2A | |
| SCHEMBL2661004 | 0.77 | RAB9A (0.34) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL2660852 | 0.77 | PLA2G7 (0.33) | MCL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1655516 | 0.76 | BRAF (0.46) | BCL2A1MCL1BCL2BIDBCL2L1 | |
| SCHEMBL2660809 | 0.76 | PLA2G7 (0.33) | MCL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |