Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722829 | 0.74 | APOBEC3A (0.42) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| Sulfuric Acid SCHEMBL28723123 | 0.73 | APOBEC3A (0.43) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| Sulfuric Acid SCHEMBL21195040 | 0.71 | APOBEC3A (0.42) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| Sulfuric Acid SCHEMBL31285729 | 0.71 | HTT (0.38) | HTTSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL21195041 | 0.70 | APOBEC3A (0.44) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| SCHEMBL28599017 | 0.70 | LMNA (0.32) | HTT | |
| Trifluoromethanesulfonic Acid SCHEMBL28396209 | 0.67 | KCNH2 (0.38) | HTTSMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL17179969 | 0.67 | HTT (0.39) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| Hydrochloric Acid SCHEMBL28638338 | 0.65 | LMNA (0.37) | HTTKDM4EAPOBEC3ASMN1; SMN2APOBEC3G | |
| SCHEMBL3003425 | 0.65 | ACHE (0.40) | HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023205615-A1 | ORALLY DISSOLVING ANTIMICROBIAL FILM COMPOSITIONS & METHODS OF THEIR USE | ISHA Therapeutics LLC (US) | 2023-10-26 | — | — | WO | disclosed |