Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15565060 | 0.85 | ALDH1A1 (0.47) | KMT2AMAPTGSK3BRAB9ANPC1 | |
| SCHEMBL28483645 | 0.80 | KMT2A (0.50) | KMT2AMEN1LMNAMAPTGSK3B | |
| SCHEMBL24634980 | 0.76 | PKM (0.56) | KMT2AMEN1LMNAMAPTRAB9A | |
| SCHEMBL28486794 | 0.75 | KMT2A (0.51) | KMT2AMEN1MAPTGSK3BRAB9A | |
| SCHEMBL2616297 | 0.73 | KMT2A (0.76) | KMT2AMEN1LMNAGSK3BALDH1A1 | |
| SCHEMBL24635088 | 0.73 | KMT2A (0.49) | KMT2AMEN1LMNAMAPTGSK3B | |
| SCHEMBL4936082 | 0.73 | MEN1 (0.75) | KMT2AMEN1LMNAMAPTNPC1 | |
| Bromide SCHEMBL6073932 | 0.71 | KMT2A (0.54) | KMT2AMEN1LMNAMAPTGSK3B | |
| SCHEMBL18825265 | 0.71 | SMN1; SMN2 (0.66) | KMT2AMEN1MAPTGSK3BRAB9A | |
| SCHEMBL14924456 | 0.70 | MEN1 (1.00) | KMT2AMEN1LMNAMAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357218-A1 | N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF | HANGZHOU WESTAN PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2023-11-09 | — | — | US | disclosed |
| CN-113214240-A | N-formamido pyrazoline derivative as P2X3 receptor antagonist and application thereof | 杭州维坦医药科技有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111892585-A | N-formamido pyrazoline derivative as P2X3 receptor antagonist and application thereof | 杭州维坦医药科技有限公司 | 2020-11-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357218-A1 | N-FORMAMIDOPYRAZOLINE DERIVATIVE AS P2X3 RECEPTOR ANTAGONIST AND USE THEREOF | P2RX3, P2RX4, P2RX7 | KMT2A 4166/4885MEN1 3136/4885LMNA 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.