Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440087 | 0.72 | — | — | |
| SCHEMBL2663972 | 0.72 | — | — | |
| SCHEMBL2663976 | 0.67 | ITGB1 (0.41) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL2845437 | 0.67 | CYP1A2 (0.42) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL17189143 | 0.63 | NLRP3 (0.57) | NFKB1NFKB2RELANLRP3 | |
| Benzoquinone SCHEMBL9318388 | 0.61 | BLM (0.47) | NFKB1 | |
| SCHEMBL13786901 | 0.59 | ALDH1A1 (0.36) | — | |
| SCHEMBL522686 | 0.59 | — | — | |
| SCHEMBL8899943 | 0.59 | NFKB1 (0.38) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL727479 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099930-A1 | Substituted Dihydroisoindolones As Allosteric Modulators of Glucokinase | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099930-A1 | Substituted Dihydroisoindolones As Allosteric Modulators of Glucokinase | GCK, GCKR, GPR119 | NFKB1 630/4885NFKB2 602/4885RELA 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.