Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302452 | 0.81 | MMP1 (0.73) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL9840923 | 0.81 | MMP1 (0.73) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL6302448 | 0.81 | MMP1 (0.73) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL725250 | 0.79 | TGM2 (0.65) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL2900749 | 0.79 | TGM2 (0.65) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL5830369 | 0.77 | TGM2 (0.63) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL9080645 | 0.77 | TGM2 (0.63) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL6581501 | 0.77 | TGM2 (0.63) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL81209 | 0.77 | TGM2 (1.00) | TGM2CYP1A2NPSR1MAOBMMP1 | |
| SCHEMBL6295972 | 0.77 | MAOB (0.79) | TGM2CYP1A2NPSR1MAOBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622358-A1 | Phenylglycinamides of 4-imidazolylmethyl-phenyl-acetic acids and their use against hypertension and atherosclerosis | BAYER AG (DE) | 1994-11-02 | — | — | EP | claimed |
| US-11040939-B1 | N-transfer reagent and method for preparing the same and its application | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2021-06-22 | — | — | US | disclosed |
| US-10800922-B2 | Pigment composition production method | KAO CORPORATION (JP) | 2020-10-13 | — | — | US | disclosed |
| WO-2017005711-A1 | PHOSPHOROUS-AND SULFUR-SUBSTITUTED BENZODIAZEPINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-12 | — | — | WO | disclosed |
| US-8273777-B2 | Glucokinase activators and methods of using same | BRISTOL-MEYER SQUIBB COMPANY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100324071-A1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | BRISTOL-MYERS SQUIBB COMPANY | 2010-12-23 | — | — | US | disclosed |
| US-7812048-B2 | Glucokinase activators and methods of using same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-12 | — | — | US | disclosed |
| US-20090030046-A1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | BRISTOL-MYERS SQUIBB COMPANY | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324071-A1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | GCKR, GCK, HK1 | TGM2 574/4885CYP1A2 3973/4885NPSR1 3043/4885 |
| US-11040939-B1 | N-transfer reagent and method for preparing the same and its application | DNTT, NNMT, NMT1 | TGM2 645/4885CYP1A2 547/4885NPSR1 1578/4885 |
| US-20090030046-A1 | NOVEL GLUCOKINASE ACTIVATORS AND METHODS OF USING SAME | GCKR, GCK, HK1 | TGM2 574/4885CYP1A2 3973/4885NPSR1 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.