Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622787 | 1.00 | BTK (0.40) | BTKCDK9CCNT1JAK3CCNK | |
| SCHEMBL26645508 | 0.91 | CDK9 (0.39) | BTKCDK9CCNT1CCNKCDK12 | |
| SCHEMBL30622918 | 0.91 | CDK9 (0.39) | BTKCDK9CCNT1CCNKCDK12 | |
| SCHEMBL30622795 | 0.85 | CSNK1E (0.42) | BTKCDK9CCNT1ALK | |
| SCHEMBL26645523 | 0.85 | CSNK1E (0.42) | BTKCDK9CCNT1ALK | |
| SCHEMBL30623067 | 0.85 | JAK1 (0.43) | JAK3CCNKCDK12MAPK1KIT | |
| SCHEMBL26645007 | 0.85 | JAK1 (0.43) | JAK3CCNKCDK12MAPK1KIT | |
| SCHEMBL30622762 | 0.84 | LIMK2 (0.36) | BTKJAK3CCNKCDK12HTR2A | |
| SCHEMBL30623059 | 0.82 | JAK1 (0.43) | BTKCDK9JAK3CCNKGPR119 | |
| SCHEMBL26645701 | 0.82 | JAK1 (0.43) | BTKCDK9JAK3CCNKGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |