Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645284 | 0.99 | MKNK1 (0.55) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645717 | 0.81 | MKNK1 (0.55) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL26645720 | 0.81 | NR1H2 (0.44) | MKNK1NR1H2KMT2AMEN1 | |
| SCHEMBL26645345 | 0.80 | CYP3A4 (0.48) | MKNK1USP30CYP3A4CYP3A5GPR119 | |
| SCHEMBL30623068 | 0.79 | GALR2 (0.53) | MKNK1NR1H2STSALDH1A1ALK | |
| SCHEMBL26645091 | 0.79 | GALR2 (0.53) | MKNK1NR1H2STSALDH1A1ALK | |
| SCHEMBL26645516 | 0.79 | NR1H2 (0.46) | GPR119NR1H2POLB | |
| SCHEMBL26645173 | 0.78 | MAPT (0.52) | GPR119NR1H2KMT2AMEN1STS | |
| SCHEMBL30622856 | 0.78 | GALR2 (0.54) | MKNK1NR1H2STSALDH1A1ALK | |
| SCHEMBL26645437 | 0.78 | GALR2 (0.54) | MKNK1NR1H2STSALDH1A1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |