Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26655299 | 0.89 | MEN1 (0.49) | KDM4EALDH1A1NPC1RAB9AMBTD1 | |
| SCHEMBL2489147 | 0.86 | L3MBTL1 (0.48) | KDM4EALDH1A1NPC1RAB9AMBTD1 | |
| SCHEMBL2490457 | 0.86 | L3MBTL1 (0.58) | KDM4EALDH1A1RAB9AMBTD1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9449150 | 0.84 | L3MBTL1 (0.57) | KDM4EALDH1A1RAB9AMBTD1L3MBTL1 | |
| SCHEMBL2489249 | 0.83 | HRH3 (0.56) | KDM4EALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL28075446 | 0.82 | HTR6 (0.44) | KDM4EALDH1A1NPC1RAB9AHTR6 | |
| Tert-Butyl Formate SCHEMBL27942745 | 0.82 | ALDH1A1 (0.42) | KDM4EALDH1A1NPC1RAB9AMBTD1 | |
| SCHEMBL4541122 | 0.82 | MEN1 (0.49) | MBTD1L3MBTL1CYP24A1HRH3MEN1 | |
| SCHEMBL9162804 | 0.81 | L3MBTL1 (0.56) | KDM4EMBTD1L3MBTL1HRH3HRH1 | |
| SCHEMBL3975042 | 0.81 | L3MBTL1 (0.49) | ALDH1A1MBTD1L3MBTL1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001875-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE | UNIV DUNDEE (GB) | 2026-01-01 | — | — | US | disclosed |
| EP-4522603-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218187-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | UNIVERSITY OF DUNDEE (GB) | 2023-11-16 | — | — | WO | disclosed |
| EP-4276097-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREAMENT OF PARKINSON'S DISEASE | University Of Dundee (GB) | 2023-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001875-A1 | AMINOPYRIMIDINYL DERIVATIVES FOR THE TREATMENT OF PARKINSON'S DISEASE | LRRK2, XIAP, PARK7 | KDM4E 1120/4885ALDH1A1 3061/4885NPC1 2775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.