SCHEMBL28075446

SCHEMBL28075446

Cc1ccc(S(=O)(=O)OCN2CCNCC2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.44
CXCR4 P61073 1/20 0.43
ADRB1 P08588 1/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
VDR P11473 1/20 0.42
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
PKM P14618 2/20 0.40
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
STAT3 P40763 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10512456 0.85 L3MBTL1 (0.50) ALDH1A1RAB9AVDRCYP2D6CYP1A2
SCHEMBL7414768 0.85 PKM (0.50) ALDH1A1RAB9AVDRCYP2D6CYP1A2
SCHEMBL1783722 0.84 KMT2A (0.50) ALDH1A1KDM4ERAB9AVDRPKM
SCHEMBL26655201 0.82 KDM4E (0.53) HTR6ALDH1A1KDM4ENPC1RAB9A
SCHEMBL5875363 0.81 VDR (0.47) HTR6ADRB1ALDH1A1KDM4EVDR
SCHEMBL26655299 0.80 MEN1 (0.49) HTR6CXCR4ALDH1A1KDM4ENPC1
SCHEMBL40765 0.79 VDR (0.46) HTR6ADRB1ALDH1A1KDM4EVDR
SCHEMBL28532973 0.77 SMN1; SMN2 (0.50) ALDH1A1KDM4ERAB9AVDRCYP2D6
Tert-Butyl Formate SCHEMBL27942745 0.76 ALDH1A1 (0.42) HTR6CXCR4ALDH1A1KDM4ENPC1
SCHEMBL14538078 0.73 ALDH1A1 (0.57) HTR6CXCR4ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103547575-B Compounds having muscarinic receptor antagonist and beta 2 adrenergic receptor agonist activity 奇斯药制品公司 2016-08-17 CN disclosed