SCHEMBL94115

SCHEMBL94115

CC1Cc2ccc(O)cc2N1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.49
MRGPRX2 Q96LB1 2/20 0.41
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
OPRK1 P41145 3/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
SIGMAR1 Q99720 2/20 0.40
DRD2 P14416 2/20 0.39
DRD3 P35462 2/20 0.39
DRD4 P21917 1/20 0.39
BRD4 O60885 4/20 0.38
CREBBP Q92793 3/20 0.38
TSHR P16473 1/20 0.38
EP300 Q09472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19289729 0.86 LMNA (0.49) ESR2MRGPRX2LMNAGAAMAPT
SCHEMBL20156702 0.86 LMNA (0.49) ESR2MRGPRX2LMNAGAAMAPT
SCHEMBL3726820 0.81 ESR2 (0.46) ESR2OPRK1OPRM1OPRD1DRD2
SCHEMBL21782466 0.78 ACHE (0.43) LMNAGAAMAPTBRD4CREBBP
SCHEMBL7920989 0.78 ACHE (0.43) LMNAGAAMAPTBRD4CREBBP
SCHEMBL21470711 0.77 TSHR (0.60) ESR2MRGPRX2LMNAGAAMAPT
SCHEMBL29051781 0.76 DRD2 (0.46) MRGPRX2OPRK1DRD2DRD3DRD4
SCHEMBL7897325 0.76 CMA1 (0.43) BRD4CREBBPTSHREP300
SCHEMBL8525664 0.76 BRD4 (0.38) LMNAGAAMAPTBRD4CREBBP
SCHEMBL2997969 0.76 ACHE (0.44) LMNAGAAMAPTBRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3113753-B2 AQUEOUS OXIDIZING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2026-03-18 EP disclosed
EP-3113753-B1 AQUEOUS OXIDIZING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2021-06-16 EP disclosed
EP-3113748-B1 PROCESS FOR MANUFACTURING AN EMULSION KAO GERMANY GMBH (DE) 2021-05-12 EP disclosed
EP-3113847-B1 ANHYDROUS DYEING COMPOSITION AND PROCESS FOR DYEING HAIR KAO GERMANY GMBH (DE) 2019-11-20 EP disclosed
EP-2346483-B1 Composition and process for treating hair KAO GERMANY GMBH (DE) 2019-04-03 EP disclosed
US-10238588-B2 Aqueous oxidizing composition for hair KAO GERMANY GMBH (DE) 2019-03-26 US disclosed
EP-3113848-B1 ANHYDROUS DYEING COMPOSITION AND PROCESS FOR DYEING HAIR KAO GERMANY GMBH (DE) 2018-10-31 EP disclosed
EP-2717848-B1 HAIR COLOURING COMPOSITION KAO GERMANY GMBH (DE) 2018-07-11 EP disclosed
EP-2022490-B1 Colouring composition KAO GERMANY GMBH (DE) 2018-06-20 EP disclosed
US-9776021-B2 Anhydrous dyeing composition and process for dyeing hair KAO GERMANY GMBH (DE) 2017-10-03 US disclosed
US-7157470-B2 Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2007-01-02 US disclosed
US-20060174424-A1 Composition for dyeing human hair KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2006-08-10 US disclosed
EP-1676605-A1 Product for hair dyeing KPSS-Kao Professional Salon Services GmbH (DE) 2006-07-05 EP disclosed
EP-1645264-A1 Product for hair dyeing in a two chamber aerosol can KPSS-Kao Professional Salon Services GmbH (DE) 2006-04-12 EP disclosed
EP-1632218-A1 Composition for dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2006-03-08 EP disclosed
EP-1627666-A1 Composition for dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2006-02-22 EP disclosed
US-20050257334-A1 Composition for dyeing keratin fibers KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US disclosed
US-20050257331-A1 Composition for dyeing of keratin fibres KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2005-11-24 US disclosed
EP-1598052-A1 Composition for bleaching and dyeing keratin fibres KPSS-Kao Professional Salon Services GmbH (DE) 2005-11-23 EP disclosed
EP-1559403-A1 Composition for dyeing human hair KPSS-Kao Professional Salon Services GmbH (DE) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060174424-A1 Composition for dyeing human hair CYB5R3, MT-ND5, COX5A ESR2 3642/4885MRGPRX2 4447/4885LMNA 1875/4885
US-20050257331-A1 Composition for dyeing of keratin fibres KRT18, KCNH3, MT-CO3 ESR2 3182/4885MRGPRX2 2781/4885LMNA 1818/4885
US-10238588-B2 Aqueous oxidizing composition for hair POLR1C, GPX4, COXFA4 ESR2 3232/4885MRGPRX2 4056/4885LMNA 1618/4885
US-20050257334-A1 Composition for dyeing keratin fibers KRT18, H1-5, CYB5R3 ESR2 3736/4885MRGPRX2 2921/4885LMNA 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.