SCHEMBL26660373

SCHEMBL26660373

CC(C)CC(NC(=O)C(C)Cc1ccccc1)C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ FCER2 P06734 5/20 0.60
▸ MMP1 P03956 4/20 0.60
▸ MME P08473 2/20 0.59
▸ CYP3A4 P08684 1/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ MMP2 P08253 1/20 0.55
▸ MMP3 P08254 1/20 0.55
▸ ERAP2 Q6P179 1/20 0.54
▸ ERAP1 Q9NZ08 1/20 0.54
▸ LNPEP Q9UIQ6 1/20 0.54
▸ LTA4H P09960 1/20 0.53
▸ REN P00797 1/20 0.53
▸ ALDH1A1 P00352 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ HSD17B10 Q99714 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24084025 0.90 MME (0.60) FCER2MMP1MMECYP3A4MAPK1
SCHEMBL27354283 0.89 FCER2 (0.67) FCER2MMP1MMEMMP2MMP3
SCHEMBL9556647 0.89 FCER2 (0.67) FCER2MMP1MMEERAP2ERAP1
SCHEMBL15223611 0.88 MME (0.74) MMECYP3A4MAPK1MMP2LTA4H
SCHEMBL12057953 0.87 LTA4H (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL31185441 0.87 LTA4H (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL12038997 0.87 LTA4H (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL2487473 0.87 LTA4H (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL30626017 0.87 LTA4H (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL7302253 0.86 FCER2 (0.61) FCER2MMP1MMEMMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11813334-B2 Polyethylene glycol conjugate drug, and preparation method therefor and use thereof Chongqing Upgra Biotechnology Co., Ltd. (CN) 2023-11-14 — — US disclosed
US-11793881-B2 Polyethylene glycol conjugate medicament, preparation method therefor and use thereof Chongqing Upgra Biotechnology Co., Ltd. (CN) 2023-10-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793881-B2 Polyethylene glycol conjugate medicament, preparation method therefor and use thereof SLC10A1, SLC10A2, NOTUM FCER2 874/4885MMP1 2275/4885MME 91/4885
US-11813334-B2 Polyethylene glycol conjugate drug, and preparation method therefor and use thereof FAR1, SLC10A1, THEM6 FCER2 1361/4885MMP1 3225/4885MME 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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