Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.36 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702638 | 0.83 | ALOX15 (0.48) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL30112000 | 0.83 | ALOX15 (0.48) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL29488827 | 0.79 | ALDH1A1 (0.46) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL4221972 | 0.79 | ALDH1A1 (0.46) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL26673061 | 0.79 | MAPK1 (0.44) | HPGDALDH1A1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL13588543 | 0.78 | ALDH1A1 (0.44) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL1105939 | 0.75 | ALDH1A1 (0.46) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL10335107 | 0.75 | ALOX15 (0.46) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL19913376 | 0.75 | ALOX15 (0.42) | ALOX15HPGDALDH1A1HSD17B10KDM4E | |
| SCHEMBL31132876 | 0.75 | KDM4E (0.51) | ALOX15HPGDALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270198-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC | 2025-08-28 | — | — | US | disclosed |
| EP-4562015-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| EP-4519250-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | D.E. Shaw Research, LLC (US) | 2025-03-12 | — | — | EP | disclosed |
| CN-119451948-A | Pyridone compounds as TRPA1 inhibitors | D·E·萧尔研究有限责任公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2023215775-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | D. E. SHAW RESEARCH, LLC (US) | 2023-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270198-A1 | PYRIDONE COMPOUNDS AS TRPA1 INHIBITORS | TRPA1, TRPV1, TRPV6 | ALOX15 111/4885HPGD 211/4885ALDH1A1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.