Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | GHSR | Q92847 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204358 | 0.75 | ALOX5 (0.40) | ALOX5NPC1RAB9APDK1SLC6A2 | |
| SCHEMBL2668587 | 0.74 | ALOX5 (0.41) | ALOX5MEN1LMNAKMT2ASLC6A2 | |
| SCHEMBL2668511 | 0.73 | NPC1 (0.41) | ALOX5MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12204197 | 0.73 | ALOX5 (0.40) | ALOX5MEN1LMNAKMT2ATSHR | |
| SCHEMBL2668512 | 0.70 | NPC1 (0.47) | ALOX5NPC1RAB9APDK1ALDH1A1 | |
| SCHEMBL8817753 | 0.69 | MEN1 (0.39) | GHSRMEN1LMNAKMT2ANPC1 | |
| SCHEMBL2668428 | 0.68 | ALDH1A1 (0.41) | ALOX5KMT2APDK1L3MBTL1ALDH1A1 | |
| SCHEMBL2668510 | 0.67 | NPSR1 (0.44) | ALOX5KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL12204347 | 0.67 | CXCR4 (0.41) | MEN1LMNAKMT2ANPSR1NPC1 | |
| SCHEMBL11138539 | 0.66 | OPRM1 (0.36) | ALOX5NPSR1NPC1RAB9APDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006814-A1 | UREA GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2007-01-18 | — | — | WO | disclosed |