Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678775 | 0.73 | CXCR3 (0.51) | EPHX2ARKCNH2SIGMAR1TP53 | |
| SCHEMBL8996650 | 0.70 | EPHX2 (0.68) | EPHX2ARKCNH2SIGMAR1 | |
| SCHEMBL9315978 | 0.64 | EPHX1 (0.67) | EPHX2CYP1A2CYP3A4CYP2C19EPHX1 | |
| SCHEMBL8874311 | 0.62 | EPHX2 (0.51) | EPHX2SIGMAR1CXCR3 | |
| SCHEMBL23921328 | 0.62 | CXCR3 (0.39) | EPHX2ARKCNH2SIGMAR1TP53 | |
| SCHEMBL25729981 | 0.61 | GRIN2D (0.33) | — | |
| SCHEMBL22939669 | 0.60 | SIGMAR1 (0.47) | EPHX2ARKCNH2SIGMAR1TP53 | |
| Hydrochloric Acid SCHEMBL9668364 | 0.59 | SIGMAR1 (0.46) | EPHX2ARKCNH2SIGMAR1TP53 | |
| SCHEMBL11698867 | 0.56 | EPHX2 (0.68) | EPHX2 | |
| SCHEMBL4110715 | 0.56 | EPHX2 (0.68) | EPHX2TP53CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346879-A1 | COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346879-A1 | COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS | RAB5IF, CLTB, TBK1 | EPHX2 2554/4885AR 4220/4885KCNH2 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.