Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 13/20 | 0.46 |
| ▸ | CTSL | P07711 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669285 | 0.88 | CTSL (0.36) | CTSSCTSLCTSKF2RL1GCK | |
| SCHEMBL2669262 | 0.88 | PSEN1 (0.51) | CTSSCTSLCTSKF2RL1PSEN1 | |
| SCHEMBL9072816 | 0.87 | CTSL (0.45) | CTSSCTSLCTSKF2RL1GCK | |
| SCHEMBL2669154 | 0.84 | CTSL (0.43) | CTSSCTSLCTSKF2RL1PSEN1 | |
| SCHEMBL2669291 | 0.84 | SMN1; SMN2 (0.45) | CTSSCTSLCTSKF2RL1GCK | |
| SCHEMBL9072791 | 0.84 | CTSL (0.41) | CTSSCTSLCTSKF2RL1GCK | |
| SCHEMBL2669300 | 0.83 | CTSL (0.43) | CTSSCTSLCTSKF2RL1GCK | |
| SCHEMBL9072817 | 0.83 | OGA (0.44) | CTSSCTSLCTSKPSEN1PSEN2 | |
| SCHEMBL2669260 | 0.82 | PSEN1 (0.43) | CTSSCTSLCTSKPSEN1PSEN2 | |
| SCHEMBL2669250 | 0.81 | PSEN1 (0.44) | CTSSCTSLCTSKF2RL1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |