Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669307 | 0.89 | OGA (0.46) | CTSLOGA | |
| SCHEMBL2669256 | 0.88 | CTSS (0.46) | CTSLCTSSCTSKF2RL1GCK | |
| SCHEMBL9072816 | 0.84 | CTSL (0.45) | CTSLCTSSCTSKUSP30F2RL1 | |
| SCHEMBL9072817 | 0.83 | OGA (0.44) | CTSLCTSSCTSKGCKOGA | |
| SCHEMBL2669291 | 0.81 | SMN1; SMN2 (0.45) | CTSLCTSSCTSKUSP30F2RL1 | |
| SCHEMBL9072791 | 0.81 | CTSL (0.41) | CTSLCTSSCTSKUSP30F2RL1 | |
| SCHEMBL2669300 | 0.81 | CTSL (0.43) | CTSLCTSSCTSKUSP30F2RL1 | |
| SCHEMBL2669260 | 0.81 | PSEN1 (0.43) | CTSLCTSSCTSKGCKOGA | |
| SCHEMBL2669154 | 0.80 | CTSL (0.43) | CTSLCTSSCTSKUSP30F2RL1 | |
| SCHEMBL2669262 | 0.79 | PSEN1 (0.51) | CTSLCTSSCTSKF2RL1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |