Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 14/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2669260 | 0.94 | PSEN1 (0.43) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2669262 | 0.92 | PSEN1 (0.51) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2669307 | 0.91 | OGA (0.46) | OGAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2669154 | 0.87 | CTSL (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2669291 | 0.84 | SMN1; SMN2 (0.45) | GCKCTSLSMN1; SMN2CTSSCTSK | |
| SCHEMBL2669250 | 0.84 | PSEN1 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2669300 | 0.83 | CTSL (0.43) | GCKCTSLCTSSCTSK | |
| SCHEMBL2669256 | 0.83 | CTSS (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL2669285 | 0.83 | CTSL (0.36) | OGAGCKCTSLCTSSCTSK | |
| SCHEMBL9072816 | 0.83 | CTSL (0.45) | GCKCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |